STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_04370Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)    
Predicted Functional Partners:
BU52_04375
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.910
BU52_00945
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.894
BU52_09685
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.893
BU52_26050
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.893
BU52_24035
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.880
BU52_23640
Multicopper oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.813
BU52_11970
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.738
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.702
BU52_09530
[Fe-S]-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.697
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.686
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.