close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_08475Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)    
Predicted Functional Partners:
BU52_08480
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.712
BU52_20820
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.707
BU52_23400
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.707
rbpA
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.699
BU52_08485
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.679
mqnB
Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.672
mqnD
1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
       0.672
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
     0.665
BU52_07505
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.655
BU52_07465
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.642
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
Server load: low (28%) [HD]