STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_12600DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)    
Predicted Functional Partners:
BU52_20790
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.989
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.985
BU52_19135
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.974
BU52_23850
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.973
BU52_15205
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.936
BU52_24950
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.917
BU52_00245
3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.902
BU52_32675
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
   
 0.896
BU52_12605
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.846
BU52_12610
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.833
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.