STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_13960IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)    
Predicted Functional Partners:
leuC
Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.849
leuD
Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.834
BU52_23400
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
BU52_13975
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.688
BU52_13980
DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
       0.658
BU52_21395
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.588
BU52_23165
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.565
BU52_21390
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.563
BU52_20820
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
BU52_07430
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.533
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.