STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_15910Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)    
Predicted Functional Partners:
BU52_08855
Replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.964
BU52_09190
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.964
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.964
BU52_18725
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.964
dnaJ-2
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.964
BU52_07015
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.852
BU52_18665
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.846
BU52_24035
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.767
BU52_22225
Mixed polyketide synthase/non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.756
BU52_16355
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.745
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.