STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_16565Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (66 aa)    
Predicted Functional Partners:
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
  0.727
BU52_20025
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.722
BU52_10575
Alcaligin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.704
BU52_24035
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.686
BU52_06330
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.573
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
    0.504
BU52_00195
Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.476
BU52_00250
Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.476
BU52_04795
Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.476
BU52_09110
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.476
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.