STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_19070Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)    
Predicted Functional Partners:
BU52_18895
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.959
BU52_18900
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.955
BU52_08190
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.771
BU52_19060
Histidine triad (HIT) protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.758
BU52_19075
16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.750
BU52_19080
2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.750
dnaJ-2
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
       0.701
hrcA
HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.701
BU52_19065
Peptidase S41; Degrades oligopeptides; Belongs to the peptidase S41B family.
       0.686
BU52_19095
Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.668
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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