STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_20600NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)    
Predicted Functional Partners:
BU52_20595
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
       0.797
BU52_20605
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.794
BU52_20575
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.724
BU52_20580
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.702
BU52_20585
Protein tyrosine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
       0.702
BU52_20590
Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.702
BU52_20565
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.697
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.689
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.677
BU52_11970
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.662
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.