STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_24780Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)    
Predicted Functional Partners:
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.995
BU52_24785
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
BU52_01490
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.814
BU52_24790
Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.713
BU52_11405
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family.
   
    0.703
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.692
BU52_24795
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.676
BU52_05865
Peptidase S54; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.636
BU52_09655
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.636
BU52_24055
Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.636
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.