STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (486 aa)    
Predicted Functional Partners:
cobN
Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
BU52_25080
Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
BU52_25110
Precorrin methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
BU52_25115
precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
BU52_25075
Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.995
BU52_25125
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.988
BU52_25090
Precorrin-2 C20-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.986
BU52_09790
Adenosylcobinamide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.979
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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