node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KIP52542.1 | KIP53048.1 | SD72_08165 | SD72_06110 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
KIP52542.1 | KIP53489.1 | SD72_08165 | SD72_01920 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.972 |
KIP52542.1 | ffh | SD72_08165 | SD72_11635 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.930 |
KIP52542.1 | ftsY | SD72_08165 | SD72_08650 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.910 |
KIP52542.1 | rplM | SD72_08165 | SD72_10410 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.677 |
KIP52542.1 | secA | SD72_08165 | SD72_12715 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.937 |
KIP52542.1 | secD | SD72_08165 | SD72_06105 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.903 |
KIP52542.1 | secE | SD72_08165 | SD72_12565 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.973 |
KIP52542.1 | secF | SD72_08165 | SD72_06100 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.876 |
KIP52542.1 | secY | SD72_08165 | SD72_10475 | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.983 |
KIP53048.1 | KIP52542.1 | SD72_06110 | SD72_08165 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
KIP53048.1 | KIP53489.1 | SD72_06110 | SD72_01920 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.970 |
KIP53048.1 | ffh | SD72_06110 | SD72_11635 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.967 |
KIP53048.1 | ftsY | SD72_06110 | SD72_08650 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.968 |
KIP53048.1 | rplM | SD72_06110 | SD72_10410 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.546 |
KIP53048.1 | secA | SD72_06110 | SD72_12715 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.967 |
KIP53048.1 | secD | SD72_06110 | SD72_06105 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.981 |
KIP53048.1 | secE | SD72_06110 | SD72_12565 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.976 |
KIP53048.1 | secF | SD72_06110 | SD72_06100 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.929 |
KIP53048.1 | secY | SD72_06110 | SD72_10475 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.960 |