STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIP52377.1Isochorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)    
Predicted Functional Partners:
menD
2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 
 0.974
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.955
KIP51278.1
Para-aminobenzoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.950
KIP51546.1
Chorismate mutase; Catalyzes the interconversion of chorismate to prephenate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.922
KIP53072.1
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.906
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
  
 0.879
KIP52083.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.877
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
     
 0.872
KIP52181.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.839
KIP52446.1
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family.
  
   
 0.818
Your Current Organism:
Leucobacter komagatae
NCBI taxonomy Id: 55969
Other names: CCUG 49676, CIP 105084, DSM 8803, IFO 15245, JCM 9414, L. komagatae, NBRC 15245, VKM Ac-2073
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