STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIP51425.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)    
Predicted Functional Partners:
KIP51330.1
Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.939
KIP51326.1
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
  
 0.905
KIP53910.1
Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
 0.872
KIP52950.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.649
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.457
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
  0.445
KIP51313.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.427
KIP52587.1
3-methyl-2-oxobutanoate hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.423
KIP52588.1
3-methyl-2-oxobutanoate hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.423
KIP52369.1
Phosphonomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.423
Your Current Organism:
Leucobacter komagatae
NCBI taxonomy Id: 55969
Other names: CCUG 49676, CIP 105084, DSM 8803, IFO 15245, JCM 9414, L. komagatae, NBRC 15245, VKM Ac-2073
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