STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A177D3L0D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (590 aa)    
Predicted Functional Partners:
AA0117_g4739
Phosphoserine aminotransferase.
 
 0.966
A0A177DFD4
P-loop containing nucleoside triphosphate hydrolase protein.
     
 0.926
AA0117_g1032
2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
 0.907
AA0117_g3989
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 
0.900
AA0117_g8971
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
     
 0.692
AA0117_g10342
Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family.
     
 0.683
A0A177D3U5
Uncharacterized protein.
  
 0.672
A0A177E1J1
MYND-type domain-containing protein.
  
 0.672
A0A177DVA2
PLP-dependent transferase.
  
 
 0.635
A0A177DNA1
Histidine biosynthesis trifunctional protein.
  
  
 0.595
Your Current Organism:
Alternaria alternata
NCBI taxonomy Id: 5599
Other names: A. alternata, ATCC 66981 [[Alternaria tenuis]], Alternaria sp. AltIEIHBT, Alternaria sp. Ao34, Alternaria sp. Ao41, Alternaria sp. JZ017, Alternaria sp. M2-2, Alternaria sp. XJU-1, Alternaria tenuis, CBS 916.96 [[Alternaria tenuis]], EGS 34-016 [[Alternaria tenuis]], IMI 254138 [[Alternaria tenuis]], Torula alternata
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