AA0117_g10363 protein (Alternaria alternata)

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Score

AA0117_g10363

Hydroxymethylglutaryl-CoA lyase. (387 aa)

Predicted Functional Partners:

AA0117_g11606

0.979

AA0117_g1109

0.976

A0A177DWK9

0.948

A0A177DSW7

0.941

A0A177D834

0.940

A0A177DDV6

0.940

A0A177DG09

0.940

A0A177DL66

0.931

A0A177DRB5

0.931

AA0117_g6800

0.930

Your Current Organism:

Alternaria alternata

NCBI taxonomy Id: 5599
Other names: A. alternata, ATCC 66981 [[Alternaria tenuis]], Alternaria sp. AltIEIHBT, Alternaria sp. Ao34, Alternaria sp. Ao41, Alternaria sp. JZ017, Alternaria sp. M2-2, Alternaria sp. XJU-1, Alternaria tenuis, CBS 916.96 [[Alternaria tenuis]], EGS 34-016 [[Alternaria tenuis]], IMI 254138 [[Alternaria tenuis]], Torula alternata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A177D834	A0A177DDV6	A0A177D834	A0A177DDV6	Fe-ADH domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.901
A0A177D834	A0A177DG09	A0A177D834	A0A177DG09	Fe-ADH domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.903
A0A177D834	A0A177DL66	A0A177D834	A0A177DL66	Fe-ADH domain-containing protein.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.941
A0A177D834	A0A177DRB5	A0A177D834	A0A177DRB5	Fe-ADH domain-containing protein.	Acetyl-CoA acetyltransferase IB; Belongs to the thiolase-like superfamily. Thiolase family.	0.941
A0A177D834	A0A177DSW7	A0A177D834	A0A177DSW7	Fe-ADH domain-containing protein.	Acetyl-coenzyme A synthetase.	0.912
A0A177D834	A0A177DWK9	A0A177D834	A0A177DWK9	Fe-ADH domain-containing protein.	Acetoacetate-CoA ligase.	0.912
A0A177D834	AA0117_g10363	A0A177D834	A0A177D706	Fe-ADH domain-containing protein.	Hydroxymethylglutaryl-CoA lyase.	0.940
A0A177D834	AA0117_g11606	A0A177D834	A0A177DXB3	Fe-ADH domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.925
A0A177D834	AA0117_g6800	A0A177D834	A0A177D993	Fe-ADH domain-containing protein.	3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	0.882
A0A177DDV6	A0A177D834	A0A177DDV6	A0A177D834	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Fe-ADH domain-containing protein.	0.901
A0A177DDV6	A0A177DG09	A0A177DDV6	A0A177DG09	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.903
A0A177DDV6	A0A177DL66	A0A177DDV6	A0A177DL66	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.941
A0A177DDV6	A0A177DRB5	A0A177DDV6	A0A177DRB5	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Acetyl-CoA acetyltransferase IB; Belongs to the thiolase-like superfamily. Thiolase family.	0.941
A0A177DDV6	A0A177DSW7	A0A177DDV6	A0A177DSW7	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Acetyl-coenzyme A synthetase.	0.912
A0A177DDV6	A0A177DWK9	A0A177DDV6	A0A177DWK9	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Acetoacetate-CoA ligase.	0.912
A0A177DDV6	AA0117_g10363	A0A177DDV6	A0A177D706	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Hydroxymethylglutaryl-CoA lyase.	0.940
A0A177DDV6	AA0117_g11606	A0A177DDV6	A0A177DXB3	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.925
A0A177DDV6	AA0117_g6800	A0A177DDV6	A0A177D993	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	0.882
A0A177DG09	A0A177D834	A0A177DG09	A0A177D834	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Fe-ADH domain-containing protein.	0.903
A0A177DG09	A0A177DDV6	A0A177DG09	A0A177DDV6	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.903

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