STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AA0117_g4037Cofilin; Belongs to the actin-binding proteins ADF family. (151 aa)    
Predicted Functional Partners:
AA0117_g4578
Actin, gamma.
   
 
 0.989
A0A177D5Z4
Tricorn protease domain 2-containing protein.
   
 
 0.988
A0A177DIF4
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.980
AA0117_g2364
Coronin; Belongs to the WD repeat coronin family.
   
 
 0.979
AA0117_g6858
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.964
AA0117_g692
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.958
AA0117_g4038
Heat shock protein 60; Belongs to the chaperonin (HSP60) family.
 
 
  
 0.951
A0A177E1H2
Actin/actin-like protein; Belongs to the actin family.
   
 
 0.923
A0A177E4S0
Actin depolymerizing protein.
    
 
 0.919
AA0117_g6059
Tropomyosin.
   
 
 0.915
Your Current Organism:
Alternaria alternata
NCBI taxonomy Id: 5599
Other names: A. alternata, ATCC 66981 [[Alternaria tenuis]], Alternaria sp. AltIEIHBT, Alternaria sp. Ao34, Alternaria sp. Ao41, Alternaria sp. JZ017, Alternaria sp. M2-2, Alternaria sp. XJU-1, Alternaria tenuis, CBS 916.96 [[Alternaria tenuis]], EGS 34-016 [[Alternaria tenuis]], IMI 254138 [[Alternaria tenuis]], Torula alternata
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