STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A177DNX0Pkinase-domain-containing protein. (661 aa)    
Predicted Functional Partners:
A0A177DQR9
RFX-type winged-helix domain-containing protein.
   
 0.974
A0A177D3F1
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.949
AA0117_g2541
BRCT domain-containing protein.
    
 0.946
AA0117_g10339
General transcriptional corepressor.
    
 0.910
A0A177DXC3
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 
 0.909
A0A177D9I5
Rhodanese domain-containing protein.
   
 0.907
AA0117_g5947
Transcriptional repressor.
    
 0.902
AA0117_g6132
Cytochrome P450 14a-demethylase; Belongs to the cytochrome P450 family.
 
      0.897
AA0117_g10507
Serine/threonine-protein kinase Chk1.
  
 
0.891
A0A177DGV6
Protein kinase domain-containing protein.
  
 
0.839
Your Current Organism:
Alternaria alternata
NCBI taxonomy Id: 5599
Other names: A. alternata, ATCC 66981 [[Alternaria tenuis]], Alternaria sp. AltIEIHBT, Alternaria sp. Ao34, Alternaria sp. Ao41, Alternaria sp. JZ017, Alternaria sp. M2-2, Alternaria sp. XJU-1, Alternaria tenuis, CBS 916.96 [[Alternaria tenuis]], EGS 34-016 [[Alternaria tenuis]], IMI 254138 [[Alternaria tenuis]], Torula alternata
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.