STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV04_07236Uncharacterized protein. (586 aa)    
Predicted Functional Partners:
PV04_07576
Protein kinase domain-containing protein.
    
 0.748
PV04_08089
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.739
PV04_10097
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
 
 0.698
PV04_09313
RPOLD domain-containing protein.
   
 0.698
PV04_05256
ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family.
   
 0.696
PV04_04423
Uncharacterized protein.
    
 
 0.689
PV04_04197
Uncharacterized protein.
   
 
 0.678
PV04_01171
Uncharacterized protein.
   
 
 0.644
PV04_09321
Uncharacterized protein; Belongs to the actin family.
    
 0.644
PV04_00909
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.635
Your Current Organism:
Phialophora americana
NCBI taxonomy Id: 5601
Other names: Cadophora americana, Capronia semi-immersa, Capronia semiimmersa, Dictyotrichiella semi-immersa, P. americana
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.