STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PV04_05328Plus3 domain-containing protein. (622 aa)    
Predicted Functional Partners:
PV04_01171
Uncharacterized protein.
   
 0.997
PV04_03282
Uncharacterized protein.
   
 0.996
PV04_06232
CDC73_C domain-containing protein.
   
 0.995
PV04_05682
Uncharacterized protein.
  
 0.992
PV04_04423
Uncharacterized protein.
   
 0.977
PV04_10097
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
 0.975
PV04_07071
Uncharacterized protein.
    
 
 0.971
PV04_00450
Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 
 0.968
PV04_06352
WD_REPEATS_REGION domain-containing protein.
    
 0.960
PV04_08163
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.952
Your Current Organism:
Phialophora americana
NCBI taxonomy Id: 5601
Other names: Cadophora americana, Capronia semi-immersa, Capronia semiimmersa, Dictyotrichiella semi-immersa, P. americana
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