Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PV04_08932ERCC4 domain-containing protein. (656 aa)    
Predicted Functional Partners:
PV04_07656
ERCC4 domain-containing protein.
  
 
 0.997
PV04_06828
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 
 0.972
PV04_00557
Uncharacterized protein.
    
 
 0.970
PV04_04124
Uncharacterized protein.
    
 
 0.968
PV04_07576
Protein kinase domain-containing protein.
    
 
 0.956
PV04_06873
Uncharacterized protein.
    
 
 0.950
PV04_06882
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
    
 
 0.946
PV04_09942
Uncharacterized protein.
    
 
 0.933
PV04_03854
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 
 0.933
PV04_05255
SMC_N domain-containing protein.
    
 
 0.921
Your Current Organism:
Phialophora americana
NCBI taxonomy Id: 5601
Other names: Cadophora americana, Capronia semi-immersa, Capronia semiimmersa, Dictyotrichiella semi-immersa, P. americana
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