STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV04_07353Uncharacterized protein. (1028 aa)    
Predicted Functional Partners:
PV04_08088
Histone H3; Belongs to the histone H3 family.
    
 0.937
PV04_08568
Histone deacetylase RPD3.
   
 0.926
PV04_02619
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.926
PV04_07938
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
 
   
  0.890
PV04_04663
WD_REPEATS_REGION domain-containing protein.
   
 0.875
PV04_04794
Uncharacterized protein.
   
 0.863
PV04_04548
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.824
PV04_01261
Tryptophan synthase.
     
 0.811
PV04_08089
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.804
PV04_05289
Histone H2A; Belongs to the histone H2A family.
    
 0.799
Your Current Organism:
Phialophora americana
NCBI taxonomy Id: 5601
Other names: Cadophora americana, Capronia semi-immersa, Capronia semiimmersa, Dictyotrichiella semi-immersa, P. americana
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.