STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV04_10777Uncharacterized protein. (297 aa)    
Predicted Functional Partners:
PV04_07402
BAH domain-containing protein.
    
 
 0.700
PV04_10132
ANK_REP_REGION domain-containing protein.
    
  0.688
PV04_10024
WD_REPEATS_REGION domain-containing protein.
    
 0.679
PV04_09204
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.676
PV04_08089
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.674
PV04_02136
Uncharacterized protein; Belongs to the OSBP family.
    
  0.661
PV04_08088
Histone H3; Belongs to the histone H3 family.
   
 0.654
PV04_03049
Uncharacterized protein.
   
 0.654
PV04_08185
Uncharacterized protein.
   
 0.654
PV04_01797
DUF2236 domain-containing protein.
   
 0.654
Your Current Organism:
Phialophora americana
NCBI taxonomy Id: 5601
Other names: Cadophora americana, Capronia semi-immersa, Capronia semiimmersa, Dictyotrichiella semi-immersa, P. americana
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.