STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV04_00905Xanthine dehydrogenase. (1359 aa)    
Predicted Functional Partners:
PV04_06015
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
  
 
 0.896
PV04_09867
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
   
 
 0.834
PV04_05383
Guanine deaminase.
 
 
 0.832
PV04_01920
Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.803
PV04_04538
Guanine deaminase.
  
 
 0.796
PV04_07534
Allophanate hydrolase.
     
 0.792
PV04_10814
Pyridoxal kinase.
     
 0.792
PV04_07182
Urea carboxylase.
     
 0.792
PV04_08191
Urea carboxylase.
     
 0.792
PV04_01163
Allophanate hydrolase.
     
 0.792
Your Current Organism:
Phialophora americana
NCBI taxonomy Id: 5601
Other names: Cadophora americana, Capronia semi-immersa, Capronia semiimmersa, Dictyotrichiella semi-immersa, P. americana
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.