Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (232 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.999
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.936
ORB07273.1
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.832
ORA98927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.811
ORB09257.1
2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.804
gcvP
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.786
ORA98923.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.748
ORA98924.1
TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.728
ORA96885.1
Fatty acyl-AMP ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.694
ORB05983.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.669
Your Current Organism:
Mycobacterium mantenii
NCBI taxonomy Id: 560555
Other names: CIP 109863, DSM 45255, JCM 18113, M. mantenii, Mycobacterium mantenii van Ingen et al. 2009, Mycobacterium sp. E152, Mycobacterium sp. E2660, Mycobacterium sp. E3078, Mycobacterium sp. E3121, Mycobacterium sp. NLA000401474, Mycobacterium sp. NLA000800224, strain NLA000401474
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