STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMF53894.15-methyltetrahydrofolate--homocysteine methyltransferase. (347 aa)    
Predicted Functional Partners:
SMF17774.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
 
 0.993
SMF17679.1
methylmalonyl-CoA mutase C-terminal domain-containing protein.
 
 0.991
SMF82358.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
 0.988
SMF82339.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.943
SMF17751.1
Methylenetetrahydrofolate reductase (NADPH).
 
 
 0.934
SMF43619.1
O-acetylhomoserine sulfhydrylase.
    
 0.852
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.830
SME89758.1
Methionine synthase (B12-independent).
  
 
 0.828
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.826
fhs
Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.817
Your Current Organism:
Tistlia consotensis
NCBI taxonomy Id: 560819
Other names: T. consotensis USBA 355, Tistlia consotensis USBA 355, alpha proteobacterium USBA 355
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