node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY79763.1 | AFY82093.1 | Oscil6304_0002 | Oscil6304_2474 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | 0.977 |
AFY79763.1 | AFY83706.1 | Oscil6304_0002 | Oscil6304_4177 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.467 |
AFY79763.1 | gyrB | Oscil6304_0002 | Oscil6304_0934 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] | 0.745 |
AFY79763.1 | pheT | Oscil6304_0002 | Oscil6304_3629 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.524 |
AFY79763.1 | polA | Oscil6304_0002 | Oscil6304_5659 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.998 |
AFY79763.1 | recF | Oscil6304_0002 | Oscil6304_5226 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.859 |
AFY79763.1 | rnhA | Oscil6304_0002 | Oscil6304_4700 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, gamma/tau subunit; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.996 |
AFY82093.1 | AFY79763.1 | Oscil6304_2474 | Oscil6304_0002 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.977 |
AFY82093.1 | gyrB | Oscil6304_2474 | Oscil6304_0934 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] | 0.736 |
AFY82093.1 | pheT | Oscil6304_2474 | Oscil6304_3629 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.642 |
AFY82093.1 | polA | Oscil6304_2474 | Oscil6304_5659 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
AFY82093.1 | recF | Oscil6304_2474 | Oscil6304_5226 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.413 |
AFY82093.1 | rnhA | Oscil6304_2474 | Oscil6304_4700 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. | DNA polymerase III, gamma/tau subunit; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.483 |
AFY83706.1 | AFY79763.1 | Oscil6304_4177 | Oscil6304_0002 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.467 |
AFY83706.1 | gyrB | Oscil6304_4177 | Oscil6304_0934 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] | 0.628 |
AFY83706.1 | miaA | Oscil6304_4177 | Oscil6304_0933 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.400 |
AFY83706.1 | pheT | Oscil6304_4177 | Oscil6304_3629 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.716 |
AFY83706.1 | polA | Oscil6304_4177 | Oscil6304_5659 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.643 |
AFY83706.1 | recF | Oscil6304_4177 | Oscil6304_5226 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.493 |
AFY84636.1 | gyrB | Oscil6304_5134 | Oscil6304_0934 | PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller. | Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] | 0.995 |