node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SED77768.1 | SEE37270.1 | SAMN04488561_0396 | SAMN04488561_1128 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ADP-ribose pyrophosphatase YjhB, NUDIX family. | 0.612 |
SED77768.1 | SEE81880.1 | SAMN04488561_0396 | SAMN04488561_2830 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.947 |
SED77768.1 | SEF09256.1 | SAMN04488561_0396 | SAMN04488561_3774 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.696 |
SED77768.1 | gcvP | SAMN04488561_0396 | SAMN04488561_3467 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.960 |
SED77768.1 | guaA | SAMN04488561_0396 | SAMN04488561_3617 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.515 |
SEE37237.1 | SEE37270.1 | SAMN04488561_1127 | SAMN04488561_1128 | Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC. | ADP-ribose pyrophosphatase YjhB, NUDIX family. | 0.566 |
SEE37270.1 | SED77768.1 | SAMN04488561_1128 | SAMN04488561_0396 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.612 |
SEE37270.1 | SEE37237.1 | SAMN04488561_1128 | SAMN04488561_1127 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC. | 0.566 |
SEE37270.1 | SEE81880.1 | SAMN04488561_1128 | SAMN04488561_2830 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.612 |
SEE37270.1 | SEF09256.1 | SAMN04488561_1128 | SAMN04488561_3774 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.509 |
SEE37270.1 | SEF10420.1 | SAMN04488561_1128 | SAMN04488561_3936 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | 5'-nucleotidase. | 0.460 |
SEE37270.1 | SEF12165.1 | SAMN04488561_1128 | SAMN04488561_4188 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | 5'-nucleotidase. | 0.491 |
SEE37270.1 | SEF16185.1 | SAMN04488561_1128 | SAMN04488561_5270 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.436 |
SEE37270.1 | gcvP | SAMN04488561_1128 | SAMN04488561_3467 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.667 |
SEE37270.1 | guaA | SAMN04488561_1128 | SAMN04488561_3617 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.491 |
SEE37270.1 | nadE | SAMN04488561_1128 | SAMN04488561_1889 | ADP-ribose pyrophosphatase YjhB, NUDIX family. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.652 |
SEE81880.1 | SED77768.1 | SAMN04488561_2830 | SAMN04488561_0396 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.947 |
SEE81880.1 | SEE37270.1 | SAMN04488561_2830 | SAMN04488561_1128 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ADP-ribose pyrophosphatase YjhB, NUDIX family. | 0.612 |
SEE81880.1 | SEF09256.1 | SAMN04488561_2830 | SAMN04488561_3774 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.696 |
SEE81880.1 | gcvP | SAMN04488561_2830 | SAMN04488561_3467 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.960 |