SEF17758.1 protein (Jiangella alba) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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[Homology]

Score

SEF17758.1

Transcriptional regulator, PaaX family. (268 aa)

Predicted Functional Partners:

SEF17755.1

0.840

SEF17752.1

0.773

SED75273.1

0.626

SED75175.1

0.608

SEF17760.1

0.562

SED75253.1

0.550

cobB

0.516

SED75219.1

0.477

SED75310.1

0.402

Your Current Organism:

Jiangella alba

NCBI taxonomy Id: 561176
Other names: CCTCC AA 208023, DSM 45237, J. alba, JCM 16901, Jiangella alba Qin et al. 2009, Jiangella sp. YIM 61503, YIM 61503

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SED75175.1	SED75219.1	SAMN04488561_0330	SAMN04488561_0331	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	0.999
SED75175.1	SED75253.1	SAMN04488561_0330	SAMN04488561_0332	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	0.998
SED75175.1	SED75273.1	SAMN04488561_0330	SAMN04488561_0333	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD.	0.996
SED75175.1	SED75310.1	SAMN04488561_0330	SAMN04488561_0334	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	0.998
SED75175.1	SEF17755.1	SAMN04488561_0330	SAMN04488561_6029	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.	0.880
SED75175.1	SEF17758.1	SAMN04488561_0330	SAMN04488561_6030	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	Transcriptional regulator, PaaX family.	0.608
SED75219.1	SED75175.1	SAMN04488561_0331	SAMN04488561_0330	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	0.999
SED75219.1	SED75253.1	SAMN04488561_0331	SAMN04488561_0332	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	0.999
SED75219.1	SED75273.1	SAMN04488561_0331	SAMN04488561_0333	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD.	0.999
SED75219.1	SED75310.1	SAMN04488561_0331	SAMN04488561_0334	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	0.999
SED75219.1	SEF17755.1	SAMN04488561_0331	SAMN04488561_6029	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.	0.876
SED75219.1	SEF17758.1	SAMN04488561_0331	SAMN04488561_6030	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	Transcriptional regulator, PaaX family.	0.477
SED75253.1	SED75175.1	SAMN04488561_0332	SAMN04488561_0330	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	0.998
SED75253.1	SED75219.1	SAMN04488561_0332	SAMN04488561_0331	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	0.999
SED75253.1	SED75273.1	SAMN04488561_0332	SAMN04488561_0333	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD.	0.997
SED75253.1	SED75310.1	SAMN04488561_0332	SAMN04488561_0334	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	0.998
SED75253.1	SEF17755.1	SAMN04488561_0332	SAMN04488561_6029	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.	0.870
SED75253.1	SEF17758.1	SAMN04488561_0332	SAMN04488561_6030	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC.	Transcriptional regulator, PaaX family.	0.550
SED75273.1	SED75175.1	SAMN04488561_0333	SAMN04488561_0330	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA.	0.996
SED75273.1	SED75219.1	SAMN04488561_0333	SAMN04488561_0331	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB.	0.999

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Network Stats

number of nodes:

9

number of edges:

18

average node degree:

4

avg. local clustering coefficient:

0.806

expected number of edges:

10

PPI enrichment p-value:

0.0125

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051301

Cell division

9 of 33

1.79

4.03

2.23e-12

GO:0008360

Regulation of cell shape

7 of 28

1.76

3.08

8.73e-09

GO:0007049

Cell cycle

7 of 31

1.71

2.98

8.73e-09

GO:0009252

Peptidoglycan biosynthetic process

6 of 24

1.76

2.77

1.11e-07

GO:0071555

Cell wall organization

6 of 31

1.65

2.46

2.73e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016881

Acid-amino acid ligase activity

4 of 14

1.82

1.65

0.00034

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032153

Cell division site

2 of 4

2.06

0.97

0.0147

GO:0005887

Integral component of plasma membrane

3 of 23

1.47

0.85

0.0147

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1512

Cell shape, and Cell division site

10 of 22

2.02

5.9

1.44e-16

CL:1516

Mur ligase, C-terminal, and PASTA domain

7 of 8

2.3

5.57

1.19e-12

CL:1506

Mixed, incl. Cell division, and Signal

11 of 85

1.47

3.04

1.97e-14

CL:1541

Septum formation initiator, and SpoVT-AbrB domain

3 of 5

2.14

1.9

0.00020

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

7 of 26

1.79

3.38

1.15e-09

map00471

D-Glutamine and D-glutamate metabolism

2 of 4

2.06

0.98

0.0140

map01502

Vancomycin resistance

2 of 9

1.71

0.75

0.0337

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032153

Cell division site

3 of 5

2.14

1.62

0.00077

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0132

Cell division

8 of 22

1.92

4.38

4.15e-12

KW-0131

Cell cycle

8 of 22

1.92

4.38

4.15e-12

KW-0573

Peptidoglycan synthesis

5 of 11

2.02

3.15

1.38e-07

KW-0133

Cell shape

5 of 11

2.02

3.15

1.38e-07

KW-0961

Cell wall biogenesis/degradation

5 of 13

1.94

3.02

1.62e-07

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02875

Mur ligase family, glutamate ligase domain

4 of 4

2.36

2.75

4.95e-06

PF08245

Mur ligase middle domain

4 of 7

2.12

2.45

1.16e-05

PF01225

Mur ligase family, catalytic domain

3 of 3

2.36

2.02

0.00015

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004101

Mur ligase, C-terminal

4 of 4

2.36

2.54

1.38e-05

IPR036615

Mur ligase, C-terminal domain superfamily

4 of 5

2.26

2.5

1.38e-05

IPR036565

Mur-like, catalytic domain superfamily

4 of 7

2.12

2.33

2.15e-05

IPR013221

Mur ligase, central

4 of 7

2.12

2.33

2.15e-05

IPR000713

Mur ligase, N-terminal catalytic domain

3 of 3

2.36

1.91

0.00025

(more ...)

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