node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SED81395.1 | SEE60092.1 | SAMN04488561_0493 | SAMN04488561_1907 | 5'-3' exonuclease. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.945 |
SED81395.1 | SEF14803.1 | SAMN04488561_0493 | SAMN04488561_4742 | 5'-3' exonuclease. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.969 |
SED81395.1 | SEF17868.1 | SAMN04488561_0493 | SAMN04488561_6089 | 5'-3' exonuclease. | Superfamily I DNA or RNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.556 |
SED81395.1 | SEF17870.1 | SAMN04488561_0493 | SAMN04488561_6090 | 5'-3' exonuclease. | DNA helicase-2 / ATP-dependent DNA helicase PcrA; Belongs to the helicase family. UvrD subfamily. | 0.556 |
SED81395.1 | SEF17881.1 | SAMN04488561_0493 | SAMN04488561_6097 | 5'-3' exonuclease. | ATP-dependent DNA helicase, Rep family. | 0.985 |
SED81395.1 | polA | SAMN04488561_0493 | SAMN04488561_0521 | 5'-3' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.602 |
SED81395.1 | recA | SAMN04488561_0493 | SAMN04488561_0368 | 5'-3' exonuclease. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.930 |
SED81395.1 | topA | SAMN04488561_0493 | SAMN04488561_5033 | 5'-3' exonuclease. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.753 |
SEE60092.1 | SED81395.1 | SAMN04488561_1907 | SAMN04488561_0493 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 5'-3' exonuclease. | 0.945 |
SEE60092.1 | SEE82941.1 | SAMN04488561_1907 | SAMN04488561_2877 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 5'-3' exonuclease. | 0.945 |
SEE60092.1 | SEF14803.1 | SAMN04488561_1907 | SAMN04488561_4742 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.953 |
SEE60092.1 | SEF17868.1 | SAMN04488561_1907 | SAMN04488561_6089 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Superfamily I DNA or RNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.806 |
SEE60092.1 | SEF17870.1 | SAMN04488561_1907 | SAMN04488561_6090 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | DNA helicase-2 / ATP-dependent DNA helicase PcrA; Belongs to the helicase family. UvrD subfamily. | 0.806 |
SEE60092.1 | SEF17881.1 | SAMN04488561_1907 | SAMN04488561_6097 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | ATP-dependent DNA helicase, Rep family. | 0.999 |
SEE60092.1 | polA | SAMN04488561_1907 | SAMN04488561_0521 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.963 |
SEE60092.1 | recA | SAMN04488561_1907 | SAMN04488561_0368 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.833 |
SEE60092.1 | topA | SAMN04488561_1907 | SAMN04488561_5033 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.578 |
SEE82941.1 | SEE60092.1 | SAMN04488561_2877 | SAMN04488561_1907 | 5'-3' exonuclease. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.945 |
SEE82941.1 | SEF14803.1 | SAMN04488561_2877 | SAMN04488561_4742 | 5'-3' exonuclease. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.969 |
SEE82941.1 | SEF17868.1 | SAMN04488561_2877 | SAMN04488561_6089 | 5'-3' exonuclease. | Superfamily I DNA or RNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.618 |