STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (441 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 0.991
EEB36794.1
DNA replication protein DnaC; KEGG: spi:MGAS10750_Spy1680 1.2e-15 replicative DNA helicase K01529; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.977
EEB35579.1
Hypothetical protein; KEGG: pfa:MAL3P8.9 0.0081 PFC0050c; long chain fatty acid ligase, putative K01897; Psort location: Cytoplasmic, score: 8.87.
  
 0.968
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.964
EEB37087.1
Hypothetical protein; KEGG: spi:MGAS10750_Spy1680 6.7e-142 replicative DNA helicase K01529; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.951
EEB36798.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.846
rplI
Ribosomal protein L9 domain protein; KEGG: chy:CHY_1571 0.0033 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.846
EEB36795.1
DnaD domain protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.838
EEB36800.1
DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
  
 0.831
EEB36796.1
Acetyltransferase, GNAT family; KEGG: wbr:WGpWb0002 5.5e-12 spermidine acetyltransferase K00657; Psort location: Cytoplasmic, score: 8.87.
  
    0.815
Your Current Organism:
Anaerococcus hydrogenalis
NCBI taxonomy Id: 561177
Other names: A. hydrogenalis DSM 7454, Anaerococcus hydrogenalis DSM 7454, Anaerococcus hydrogenalis GIFU 7662, Anaerococcus hydrogenalis str. DSM 7454, Anaerococcus hydrogenalis strain DSM 7454
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