STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLKEGG: cno:NT01CX_0259 2.3e-132 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 8.87. (418 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; KEGG: cno:NT01CX_0260 2.9e-109 hemB; delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 8.87; Belongs to the ALAD family.
 
 
 0.997
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 6.8e-62 uroporphyrinogen III synthase/methyltransferase K00589; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.994
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.992
EEB36698.1
Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.988
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.976
EEB36695.1
Siroheme synthase domain protein; KEGG: mja:MJ0140 1.4e-13 precorrin-2 oxidase / ferrochelatase K02303:K02304; Psort location: Cytoplasmic, score: 8.87.
    
 0.827
EEB36784.1
KEGG: cno:NT01CX_0234 5.8e-136 citrate synthase I K01647; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.668
metAA
Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
   
  
 0.614
EEB35771.1
Putative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
    0.602
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.568
Your Current Organism:
Anaerococcus hydrogenalis
NCBI taxonomy Id: 561177
Other names: A. hydrogenalis DSM 7454, Anaerococcus hydrogenalis DSM 7454, Anaerococcus hydrogenalis GIFU 7662, Anaerococcus hydrogenalis str. DSM 7454, Anaerococcus hydrogenalis strain DSM 7454
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