STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1339 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
 
 0.999
rbpA
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
    
 
 0.999
EFA23762.1
Hypothetical protein; KEGG: btk:BT9727_2572 5.8e-28 uvrD; UvrD/Rep helicase family protein K01529; Psort location: Cytoplasmic, score: 8.87.
    
 
 0.999
EFA23787.1
Sigma-70 region 2; KEGG: reh:H16_A2563 1.2e-14 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
    
 
 0.999
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 0.999
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 0.999
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 0.999
EFA22151.1
CarD-like protein; Psort location: Cytoplasmic, score: 8.87.
    
 
 0.999
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
   0.996
greA
Prokaryotic transcription elongation factor, GreA/GreB domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
 
 0.994
Your Current Organism:
Bifidobacterium gallicum
NCBI taxonomy Id: 561180
Other names: B. gallicum DSM 20093 = LMG 11596, Bifidobacterium gallicum DSM 20093, Bifidobacterium gallicum DSM 20093 = LMG 11596, Bifidobacterium gallicum JCM 8224, Bifidobacterium gallicum LMG 11596, Bifidobacterium gallicum LMG 11596 = DSM 20093
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