STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argSarginine--tRNA ligase; KEGG: blo:BL1272 5.3e-245 argS; arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.98. (631 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
   
  
 0.987
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
 0.964
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 0.948
leuS
leucine--tRNA ligase; KEGG: blo:BL1450 0. leuS; leucyl-tRNA synthetase K01869; Psort location: Cytoplasmic, score: 9.65; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 0.948
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
  
 0.940
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.897
pheT
phenylalanine--tRNA ligase, beta subunit; KEGG: blo:BL1066 0. pheT; phenylalanyl-tRNA synthetase beta chain K01890; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.889
lysS
lysine--tRNA ligase; KEGG: blo:BL1654 1.6e-257 lysS; lysyl-tRNA synthetase 1 K04567; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.885
EFA22494.1
tRNA ligase class I (E and Q), catalytic domain protein; KEGG: ade:Adeh_0295 2.5e-41 glutamate--tRNA ligase K01885; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 0.865
tyrS
tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
  
  
 0.822
Your Current Organism:
Bifidobacterium gallicum
NCBI taxonomy Id: 561180
Other names: B. gallicum DSM 20093 = LMG 11596, Bifidobacterium gallicum DSM 20093, Bifidobacterium gallicum DSM 20093 = LMG 11596, Bifidobacterium gallicum JCM 8224, Bifidobacterium gallicum LMG 11596, Bifidobacterium gallicum LMG 11596 = DSM 20093
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