STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (248 aa)    
Predicted Functional Partners:
MinD
Septum site-determining protein MinD.
 
 0.999
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
  
 0.966
SDC63526.1
Rod shape-determining protein MreC.
  
  
 0.863
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.819
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
  
  
 0.558
MreB
Rod shape-determining protein MreB.
  
  
 0.454
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
  
 0.453
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
   
  
 0.442
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
  
    0.441
SDC78414.1
DNA modification methylase.
   
  
 0.440
Your Current Organism:
Mameliella alba
NCBI taxonomy Id: 561184
Other names: Alkalimicrobium pacificum, Alkalimicrobium pacificum Zhang et al. 2015, Antarctobacter sp. JLT354-W, CGMCC 1.12763 [[Alkalimicrobium pacificum]], CGMCC 1.12986 [[Ponticoccus lacteus]], CGMCC 1.7290, JCM 19851 [[Alkalimicrobium pacificum]], JCM 30230 [[Mameliella atlantica]], JCM 30379 [[Ponticoccus lacteus]], KCTC 42178 [[Mameliella phaeodactyli]], LMG 24665, LMG 28107 [[Alkalimicrobium pacificum]], LMG:24665, LMG:28107 [[Alkalimicrobium pacificum]], M. alba, MCCC 1A07531 [[Mameliella atlantica]], MCCC 1A09948 [[Alkalimicrobium pacificum]], MCCC 1K00273 [[Mameliella phaeodactyli]], Mameliella alba Zheng et al. 2010 emend. Liu et al. 2018, Mameliella atlantica, Mameliella atlantica Xu et al. 2015, Mameliella phaeodactyli, Mameliella phaeodactyli Chen et al. 2015, Mameliella sp. L6M1-5, Ponticoccus lacteus, Ponticoccus lacteus Yang et al. 2015, Ponticoccus sp. UMTAT08, Rhodobacteraceae bacterium F15, Rhodobacteraceae bacterium KD53, Roseobacter sp. JL-351, proteobacterium JL351, strain F15 [[Alkalimicrobium pacificum]], strain JL351 [[Ponticoccus lacteus]], strain JLT354-W, strain KD53 [[Mameliella phaeodactyli]], strain L6M1-5 [[Mameliella atlantica]]
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