STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
lgtPhosphatidylglycerol:prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (303 aa)    
Predicted Functional Partners:
SDD10361.1
Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
 
     0.891
SDD10335.1
SAM-dependent methyltransferase, MidA family.
 
     0.885
yidC
YidC/Oxa1 family membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
  
 0.819
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.807
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.796
SDD10294.1
BMFP domain-containing protein YqiC.
       0.717
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
    
 0.710
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.684
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
    0.643
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
 
  
 0.565
Your Current Organism:
Mameliella alba
NCBI taxonomy Id: 561184
Other names: Alkalimicrobium pacificum, Alkalimicrobium pacificum Zhang et al. 2015, Antarctobacter sp. JLT354-W, CGMCC 1.12763 [[Alkalimicrobium pacificum]], CGMCC 1.12986 [[Ponticoccus lacteus]], CGMCC 1.7290, JCM 19851 [[Alkalimicrobium pacificum]], JCM 30230 [[Mameliella atlantica]], JCM 30379 [[Ponticoccus lacteus]], KCTC 42178 [[Mameliella phaeodactyli]], LMG 24665, LMG 28107 [[Alkalimicrobium pacificum]], LMG:24665, LMG:28107 [[Alkalimicrobium pacificum]], M. alba, MCCC 1A07531 [[Mameliella atlantica]], MCCC 1A09948 [[Alkalimicrobium pacificum]], MCCC 1K00273 [[Mameliella phaeodactyli]], Mameliella alba Zheng et al. 2010 emend. Liu et al. 2018, Mameliella atlantica, Mameliella atlantica Xu et al. 2015, Mameliella phaeodactyli, Mameliella phaeodactyli Chen et al. 2015, Mameliella sp. L6M1-5, Ponticoccus lacteus, Ponticoccus lacteus Yang et al. 2015, Ponticoccus sp. UMTAT08, Rhodobacteraceae bacterium F15, Rhodobacteraceae bacterium KD53, Roseobacter sp. JL-351, proteobacterium JL351, strain F15 [[Alkalimicrobium pacificum]], strain JL351 [[Ponticoccus lacteus]], strain JLT354-W, strain KD53 [[Mameliella phaeodactyli]], strain L6M1-5 [[Mameliella atlantica]]
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