STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aroE_1Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (277 aa)    
Predicted Functional Partners:
aroK_2
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 0.996
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.980
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.977
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 
 0.944
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 0.923
SDE18961.1
Shikimate dehydrogenase.
  
  
 
0.923
aroE_2
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 
0.922
SDD56505.1
Septum formation protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
 0.912
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
 0.877
dnaQ
DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
     
 0.831
Your Current Organism:
Mameliella alba
NCBI taxonomy Id: 561184
Other names: Alkalimicrobium pacificum, Alkalimicrobium pacificum Zhang et al. 2015, Antarctobacter sp. JLT354-W, CGMCC 1.12763 [[Alkalimicrobium pacificum]], CGMCC 1.12986 [[Ponticoccus lacteus]], CGMCC 1.7290, JCM 19851 [[Alkalimicrobium pacificum]], JCM 30230 [[Mameliella atlantica]], JCM 30379 [[Ponticoccus lacteus]], KCTC 42178 [[Mameliella phaeodactyli]], LMG 24665, LMG 28107 [[Alkalimicrobium pacificum]], LMG:24665, LMG:28107 [[Alkalimicrobium pacificum]], M. alba, MCCC 1A07531 [[Mameliella atlantica]], MCCC 1A09948 [[Alkalimicrobium pacificum]], MCCC 1K00273 [[Mameliella phaeodactyli]], Mameliella alba Zheng et al. 2010 emend. Liu et al. 2018, Mameliella atlantica, Mameliella atlantica Xu et al. 2015, Mameliella phaeodactyli, Mameliella phaeodactyli Chen et al. 2015, Mameliella sp. L6M1-5, Ponticoccus lacteus, Ponticoccus lacteus Yang et al. 2015, Ponticoccus sp. UMTAT08, Rhodobacteraceae bacterium F15, Rhodobacteraceae bacterium KD53, Roseobacter sp. JL-351, proteobacterium JL351, strain F15 [[Alkalimicrobium pacificum]], strain JL351 [[Ponticoccus lacteus]], strain JLT354-W, strain KD53 [[Mameliella phaeodactyli]], strain L6M1-5 [[Mameliella atlantica]]
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