STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HupVHydrogenase large subunit. (477 aa)    
Predicted Functional Partners:
HupU
Ferredoxin hydrogenase small subunit.
 0.999
HupS
Hydrogenase small subunit.
 0.998
HupT
Two-component system, NtrC family, sensor histidine kinase HupT/HoxJ.
 
 
 0.994
HupC
Ni/Fe-hydrogenase 1 B-type cytochrome subunit.
 
 
 0.985
SDD74189.1
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.972
HupL
Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
0.960
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.936
HupD
Hydrogenase maturation protease.
 
 
 0.912
HupG
Hydrogenase-1 operon protein HyaE; Belongs to the HupG/HyaE family.
 
 
 0.907
HupH
Hydrogenase-1 operon protein HyaF.
 
  
 0.903
Your Current Organism:
Mameliella alba
NCBI taxonomy Id: 561184
Other names: Alkalimicrobium pacificum, Alkalimicrobium pacificum Zhang et al. 2015, Antarctobacter sp. JLT354-W, CGMCC 1.12763 [[Alkalimicrobium pacificum]], CGMCC 1.12986 [[Ponticoccus lacteus]], CGMCC 1.7290, JCM 19851 [[Alkalimicrobium pacificum]], JCM 30230 [[Mameliella atlantica]], JCM 30379 [[Ponticoccus lacteus]], KCTC 42178 [[Mameliella phaeodactyli]], LMG 24665, LMG 28107 [[Alkalimicrobium pacificum]], LMG:24665, LMG:28107 [[Alkalimicrobium pacificum]], M. alba, MCCC 1A07531 [[Mameliella atlantica]], MCCC 1A09948 [[Alkalimicrobium pacificum]], MCCC 1K00273 [[Mameliella phaeodactyli]], Mameliella alba Zheng et al. 2010 emend. Liu et al. 2018, Mameliella atlantica, Mameliella atlantica Xu et al. 2015, Mameliella phaeodactyli, Mameliella phaeodactyli Chen et al. 2015, Mameliella sp. L6M1-5, Ponticoccus lacteus, Ponticoccus lacteus Yang et al. 2015, Ponticoccus sp. UMTAT08, Rhodobacteraceae bacterium F15, Rhodobacteraceae bacterium KD53, Roseobacter sp. JL-351, proteobacterium JL351, strain F15 [[Alkalimicrobium pacificum]], strain JL351 [[Ponticoccus lacteus]], strain JLT354-W, strain KD53 [[Mameliella phaeodactyli]], strain L6M1-5 [[Mameliella atlantica]]
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