| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACT04896.1 | ACT07049.1 | Dd1591_0002 | Dd1591_2206 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: spe:Spro_2715 exonuclease III. | 0.886 |
| ACT04896.1 | ACT08028.1 | Dd1591_0002 | Dd1591_3206 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.843 |
| ACT04896.1 | mutL | Dd1591_0002 | Dd1591_0490 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.943 |
| ACT07049.1 | ACT04896.1 | Dd1591_2206 | Dd1591_0002 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: spe:Spro_2715 exonuclease III. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.886 |
| ACT07049.1 | ACT08028.1 | Dd1591_2206 | Dd1591_3206 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: spe:Spro_2715 exonuclease III. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.878 |
| ACT08028.1 | ACT04896.1 | Dd1591_3206 | Dd1591_0002 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.843 |
| ACT08028.1 | ACT07049.1 | Dd1591_3206 | Dd1591_2206 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: spe:Spro_2715 exonuclease III. | 0.878 |
| ACT08028.1 | ACT08029.1 | Dd1591_3206 | Dd1591_3207 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.850 |
| ACT08028.1 | mltC | Dd1591_3206 | Dd1591_3208 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.713 |
| ACT08028.1 | mutL | Dd1591_3206 | Dd1591_0490 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.634 |
| ACT08028.1 | mutM | Dd1591_3206 | Dd1591_3957 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.606 |
| ACT08028.1 | recO | Dd1591_3206 | Dd1591_1070 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.631 |
| ACT08028.1 | sfsA | Dd1591_3206 | Dd1591_1033 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; KEGG: eca:ECA3316 sugar fermentation stimulation protein A; Belongs to the SfsA family. | 0.930 |
| ACT08028.1 | trmB | Dd1591_3206 | Dd1591_3205 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.657 |
| ACT08028.1 | trpF | Dd1591_3206 | Dd1591_2175 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Indole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: eca:ECA2299 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. | 0.600 |
| ACT08029.1 | ACT08028.1 | Dd1591_3207 | Dd1591_3206 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.850 |
| ACT08029.1 | mltC | Dd1591_3207 | Dd1591_3208 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.747 |
| ACT08029.1 | trmB | Dd1591_3207 | Dd1591_3205 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.652 |
| mltC | ACT08028.1 | Dd1591_3208 | Dd1591_3206 | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.713 |
| mltC | ACT08029.1 | Dd1591_3208 | Dd1591_3207 | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.747 |
