Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PC1_0073PFAM: cellulose synthase operon C domain protein; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: eca:ECA4374 cellulose synthase subunit BcsC. (1164 aa)    
Predicted Functional Partners:
PC1_0075
Cellulose synthase subunit B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.
 
 
 0.981
PC1_0074
Cellulase; PFAM: glycoside hydrolase family 8; KEGG: eca:ECA4373 endo-1,4-D-glucanase; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
 
  
 0.971
PC1_0076
Cellulose synthase catalytic subunit (UDP-forming); Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
 
  
 0.949
PC1_0077
TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: YhjQ family protein; KEGG: eca:ECA4369 hypothetical protein.
 
  
 0.948
PC1_1853
KEGG: eca:ECA2459 carboxy-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family.
  
 
 0.904
PC1_0081
TIGRFAM: cellulose synthase operon protein YhjU; KEGG: eca:ECA4364 hypothetical protein.
 
  
 0.864
PC1_0079
TIGRFAM: cellulose biosynthesis protein BcsE; KEGG: eca:ECA4366 hypothetical protein.
 
   
 0.857
PC1_2600
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: eca:ECA1700 anti-sigma28 factor FlgM.
  
 
   0.672
PC1_1117
PFAM: YfaZ family protein; KEGG: eca:ECA1217 hypothetical protein.
  
     0.653
sbmC
Transcription activator effector binding; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
  
    0.647
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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