| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PC1_0251 | PC1_0301 | PC1_0251 | PC1_0301 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | 0.868 |
| PC1_0251 | PC1_0371 | PC1_0251 | PC1_0371 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: plu:plu2006 hypothetical protein. | 0.614 |
| PC1_0251 | PC1_0372 | PC1_0251 | PC1_0372 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Putative PAS/PAC sensor protein; PFAM: PAS fold-4 domain protein; KEGG: plu:plu0925 hypothetical protein. | 0.614 |
| PC1_0251 | PC1_1449 | PC1_0251 | PC1_1449 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: eca:ECA1568 putative chemotaxis signal transduction protein. | 0.722 |
| PC1_0251 | PC1_3367 | PC1_0251 | PC1_3367 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eca:ECA3549 putative signaling protein. | 0.951 |
| PC1_0251 | PC1_3391 | PC1_0251 | PC1_3391 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA3571 hybrid sensory histidine kinase BarA. | 0.930 |
| PC1_0251 | PC1_3663 | PC1_0251 | PC1_3663 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Diguanylate cyclase; KEGG: eca:ECA3886 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. | 0.868 |
| PC1_0251 | rcsC | PC1_0251 | PC1_1106 | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | Histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.728 |
| PC1_0301 | PC1_0251 | PC1_0301 | PC1_0251 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | 0.868 |
| PC1_0301 | PC1_0371 | PC1_0301 | PC1_0371 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: plu:plu2006 hypothetical protein. | 0.678 |
| PC1_0301 | PC1_0372 | PC1_0301 | PC1_0372 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | Putative PAS/PAC sensor protein; PFAM: PAS fold-4 domain protein; KEGG: plu:plu0925 hypothetical protein. | 0.678 |
| PC1_0301 | PC1_0572 | PC1_0301 | PC1_0572 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 0.786 |
| PC1_0301 | PC1_0578 | PC1_0301 | PC1_0578 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.811 |
| PC1_0301 | PC1_1449 | PC1_0301 | PC1_1449 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: eca:ECA1568 putative chemotaxis signal transduction protein. | 0.979 |
| PC1_0301 | PC1_3367 | PC1_0301 | PC1_3367 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eca:ECA3549 putative signaling protein. | 0.988 |
| PC1_0301 | PC1_3391 | PC1_0301 | PC1_3391 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA3571 hybrid sensory histidine kinase BarA. | 0.992 |
| PC1_0301 | PC1_3663 | PC1_0301 | PC1_3663 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | Diguanylate cyclase; KEGG: eca:ECA3886 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. | 0.985 |
| PC1_0301 | rcsC | PC1_0301 | PC1_1106 | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | Histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.991 |
| PC1_0371 | PC1_0251 | PC1_0371 | PC1_0251 | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: plu:plu2006 hypothetical protein. | KEGG: eca:ECA0266 regulatory protein CsrD; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. | 0.614 |
| PC1_0371 | PC1_0301 | PC1_0371 | PC1_0301 | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: plu:plu2006 hypothetical protein. | Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein. | 0.678 |