Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PC1_0937KEGG: eca:ECA1027 hypothetical protein; Belongs to the UPF0325 family. (129 aa)    
Predicted Functional Partners:
crl
Transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.
  
     0.710
PC1_3419
PFAM: protein of unknown function DUF1107; KEGG: eca:ECA3599 hypothetical protein.
  
  
 0.703
PC1_2442
PFAM: LPP repeat-containing protein; KEGG: eca:ECA1866 major outer membrane lipoprotein.
  
     0.686
wzyE
WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.
  
     0.665
PC1_2014
KEGG: eca:ECA2287 hypothetical protein.
  
     0.662
PC1_1045
PFAM: Uncharacterized lipoprotein; KEGG: eca:ECA1145 hypothetical protein.
  
     0.648
PC1_1094
PFAM: GumN family protein; KEGG: eca:ECA1192 hypothetical protein.
  
     0.625
wecD
TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.
  
     0.615
wecF
4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.
  
     0.604
viaA
SMART: von Willebrand factor type A; KEGG: eca:ECA0004 hypothetical protein.
  
     0.597
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.