Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PC1_1124PFAM: protein of unknown function DUF214; KEGG: eca:ECA1224 hypothetical protein. (809 aa)    
Predicted Functional Partners:
PC1_1122
Lysophospholipase; PFAM: lipolytic protein G-D-S-L family; KEGG: eca:ECA1222 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1.
 
 
   0.967
PC1_1123
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_1158 putative ABC transporter ATP-binding protein YbbA.
 
 
 
 0.966
PC1_1463
KEGG: eca:ECA1578 hypothetical protein.
 
     0.724
PC1_1121
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA1221 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.571
macB
ABC transporter related; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.536
PC1_1376
PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
  
  
 0.536
lolD
Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
  
 0.495
arnE
Small multidrug resistance protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.
  
     0.435
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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