STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msbALipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (597 aa)    
Predicted Functional Partners:
PC1_1431
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1556 putative sulfate ester transporter, ATP-binding component.
 
    
0.889
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
  
 0.888
PC1_1768
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase domain protein; KEGG: eca:ECA2558 hypothetical protein.
     
 0.815
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
     0.670
PC1_0578
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.616
PC1_0572
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase.
  
 
 0.561
PC1_1771
PFAM: protein of unknown function DUF343; KEGG: eca:ECA2555 hypothetical protein; Belongs to the UPF0434 family.
       0.548
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.546
PC1_3062
Type I secretion system ATPase; KEGG: eca:ECA3268 putative toxin secretion ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 
0.470
PC1_0992
KEGG: eca:ECA1097 putative type I secretion protein, ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.
 
 
 
0.468
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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