STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PC1_1900PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA2410 putative sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (464 aa)    
Predicted Functional Partners:
cysJ
Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family.
   
  
 0.639
PC1_4179
Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
   
    0.600
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
   
    0.593
PC1_1901
PFAM: membrane-bound metal-dependent hydrolase; KEGG: eca:ECA2409 hypothetical protein.
     
 0.583
PC1_0546
PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; molybdopterin oxidoreductase Fe4S4 region; FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: mfa:Mfla_0317 sulfite reductase (NADPH) alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
   
    0.573
cysD
TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: eca:ECA3543 sulfate adenylyltransferase subunit 2.
   
  
 0.554
PC1_0765
TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA0883 thiosulfate transporter subunit.
   
    0.516
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
    0.472
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
   
  
 0.452
PC1_1012
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
  
   
 0.424
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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