Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PC1_2000PFAM: OmpW family protein; KEGG: eca:ECA2303 outer membrane protein W. (210 aa)    
Predicted Functional Partners:
PC1_4224
KEGG: eca:ECA0026 coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
  
 0.722
PC1_2750
KEGG: eca:ECA3009 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.679
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
      
 0.514
PC1_2106
PFAM: UspA domain protein; KEGG: eca:ECA2206 universal stress protein UspE.
 
  
 0.506
PC1_0862
PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: kpe:KPK_4973 Appr-1-p processing enzyme family domain protein.
   
    0.468
PC1_2824
PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: eca:ECA3081 long-chain fatty acid outer membrane transporter.
  
   
 0.457
PC1_3455
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.456
dksA
Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
   
  
 0.429
PC1_4017
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
 
   
 0.423
PC1_1999
PFAM: protein of unknown function UPF0153; KEGG: sea:SeAg_B1413 hypothetical protein.
       0.420
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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