Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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PC1_2201Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: eca:ECA2090 sigma-54-dependent enhancer-binding protein. (352 aa)    
Predicted Functional Partners:
PC1_0274
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.808
PC1_4221
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; KEGG: eca:ECA0028 nitrogen regulation protein NR(II).
 
 
 0.650
PC1_3391
Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA3571 hybrid sensory histidine kinase BarA.
  
 
 0.581
PC1_3663
Diguanylate cyclase; KEGG: eca:ECA3886 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
  
 
 0.534
PC1_2582
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.521
PC1_0301
Multi-sensor hybrid histidine kinase; KEGG: eca:ECA0314 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein.
  
 
 0.503
PC1_2581
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
  
 0.494
PC1_2203
KEGG: eca:ECA2088 two-component sensor kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein.
   
 
 0.493
PC1_2211
TIGRFAM: type III secretion system apparatus protein YscQ/HrcQ; PFAM: surface presentation of antigens (SPOA) protein; KEGG: eca:ECA2080 type III secretion protein.
  
  
 0.489
PC1_2202
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: eca:ECA2089 two-component response regulator.
   
 
 0.485
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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