Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PC1_2369KEGG: eca:ECA1954 putative transcriptional regulator. (81 aa)    
Predicted Functional Partners:
PC1_1467
PFAM: AIG2 family protein; KEGG: kpe:KPK_2039 hypothetical protein.
  
     0.551
PC1_0329
PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: kpe:KPK_1035 TonB-dependent receptor.
  
     0.545
PC1_2176
TIGRFAM: adhesin HecA family; PFAM: protein of unknown function DUF638 hemagglutinin/hemolysin putative; Haemagluttinin repeat-containing protein; KEGG: eca:ECA2118 hemolysin/hemagglutinin-like protein HecA precursor.
  
     0.528
PC1_2735
PFAM: Nitrate and nitrite sensing domain protein; ANTAR domain protein; KEGG: eca:ECA2995 nitrate-and nitrite-responsive positive regulator.
  
     0.487
PC1_0753
Transcriptional regulator, DeoR family; PFAM: putative sugar-binding domain protein; KEGG: kpe:KPK_3434 putative sugar-binding domain protein.
  
     0.477
lapA
Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
       0.452
PC1_0842
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ent:Ent638_2354 AraC family transcriptional regulator.
  
     0.451
PC1_2675
KEGG: bja:bll2387 hypothetical protein.
  
     0.448
lapB
Tetratricopeptide TPR_2 repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
       0.444
PC1_2703
PFAM: MltA-interacting MipA family protein; KEGG: pfl:PFL_0321 hypothetical protein.
  
     0.424
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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