Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
btuDABC transporter related; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (258 aa)    
Predicted Functional Partners:
btuC
Transport system permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
 
 
 0.997
btuF
Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
  
 
 0.940
btuE
Peroxiredoxin; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.
  
  
 0.917
PC1_1344
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1468 ABC transporter, ATP-binding protein.
  
     0.576
fbpC-2
ABC transporter related; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
  
     0.526
PC1_2466
PFAM: NLP/P60 protein; KEGG: eca:ECA1835 lipoprotein.
       0.503
PC1_1428
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1552 ABC transporter ATP-binding protein.
  
     0.481
PC1_2461
PFAM: transport system permease protein; KEGG: eca:ECA1844 hemin transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
   
 0.479
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
  
     0.447
PC1_0173
PFAM: transport system permease protein; KEGG: eca:ECA4256 putative iron(III) ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
   
 0.442
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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