STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PC1_2544PFAM: UvrD/REP helicase; KEGG: eca:ECA1756 DNA helicase IV. (685 aa)    
Predicted Functional Partners:
PC1_0451
KEGG: eca:ECA0466 hypothetical protein.
  
     0.770
lpoB
Membrane lipoprotein lipid attachment site; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
  
     0.770
PC1_0612
DNA polymerase III psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.768
PC1_1844
PFAM: protein of unknown function DUF1471; KEGG: eca:ECA2468 hypothetical protein.
  
     0.765
PC1_0960
Transcriptional antiterminator, Rof; PFAM: Modulator of Rho-dependent transcription termination; KEGG: eca:ECA1050 Rho-binding antiterminator.
  
     0.759
PC1_2291
KEGG: eca:ECA2003 hypothetical protein.
 
     0.759
ftsN
Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.755
PC1_1784
PFAM: porin Gram-negative type; KEGG: eca:ECA2542 outer membrane protein; Belongs to the Gram-negative porin family.
  
   
 0.751
PC1_0022
PFAM: protein of unknown function DUF1471; KEGG: eca:ECA4414 hypothetical protein.
  
     0.749
rcsD
Hpt sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
     0.746
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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