node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_1069 | PC1_2690 | PC1_1069 | PC1_2690 | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.730 |
PC1_1259 | PC1_2690 | PC1_1259 | PC1_2690 | TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1383 cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.580 |
PC1_1376 | PC1_2690 | PC1_1376 | PC1_2690 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.778 |
PC1_1376 | macB | PC1_1376 | PC1_0769 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | ABC transporter related; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.918 |
PC1_2677 | PC1_2690 | PC1_2677 | PC1_2690 | PFAM: acriflavin resistance protein; KEGG: eca:ECA2929 putative efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.853 |
PC1_2689 | PC1_2690 | PC1_2689 | PC1_2690 | PFAM: acriflavin resistance protein; KEGG: bbt:BBta_0808 RND family mulitdrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.967 |
PC1_2689 | PC1_2691 | PC1_2689 | PC1_2691 | PFAM: acriflavin resistance protein; KEGG: bbt:BBta_0808 RND family mulitdrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | PFAM: MltA-interacting MipA family protein; KEGG: xac:XAC2801 hypothetical protein. | 0.693 |
PC1_2690 | PC1_1069 | PC1_2690 | PC1_1069 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | 0.730 |
PC1_2690 | PC1_1259 | PC1_2690 | PC1_1259 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1383 cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.580 |
PC1_2690 | PC1_1376 | PC1_2690 | PC1_1376 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | 0.778 |
PC1_2690 | PC1_2677 | PC1_2690 | PC1_2677 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: acriflavin resistance protein; KEGG: eca:ECA2929 putative efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.853 |
PC1_2690 | PC1_2689 | PC1_2690 | PC1_2689 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: acriflavin resistance protein; KEGG: bbt:BBta_0808 RND family mulitdrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.967 |
PC1_2690 | PC1_2691 | PC1_2690 | PC1_2691 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: MltA-interacting MipA family protein; KEGG: xac:XAC2801 hypothetical protein. | 0.693 |
PC1_2690 | PC1_3923 | PC1_2690 | PC1_3923 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA4131 aminoglycoside/multidrug efflux system. | 0.726 |
PC1_2690 | macB | PC1_2690 | PC1_0769 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter related; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.778 |
PC1_2690 | mdtB | PC1_2690 | PC1_2967 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: acriflavin resistance protein; KEGG: eca:ECA3185 multidrug efflux system subunit MdtB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. | 0.576 |
PC1_2690 | mdtC | PC1_2690 | PC1_2968 | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: acriflavin resistance protein; KEGG: eca:ECA3186 multidrug efflux system subunit MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. | 0.577 |
PC1_2691 | PC1_2689 | PC1_2691 | PC1_2689 | PFAM: MltA-interacting MipA family protein; KEGG: xac:XAC2801 hypothetical protein. | PFAM: acriflavin resistance protein; KEGG: bbt:BBta_0808 RND family mulitdrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.693 |
PC1_2691 | PC1_2690 | PC1_2691 | PC1_2690 | PFAM: MltA-interacting MipA family protein; KEGG: xac:XAC2801 hypothetical protein. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.693 |
PC1_3923 | PC1_2690 | PC1_3923 | PC1_2690 | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA4131 aminoglycoside/multidrug efflux system. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.726 |